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An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives, by Matt Richtel
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Review
“One of those rare nonfiction books that transcends the genre. ... A fascinating and engrossing account of the latest, and quite astonishing, discoveries involving the human immune system. ... An inspiring and wonderful read. ... I highly recommend this extraordinary book.” (DOUGLAS PRESTON, #1 bestselling author of The Lost City of the Monkey God)“Deeply affecting. … A compelling modern history of—as well as an elegant defense for—the preeminent science of our time.” (Los Angeles Review of Books)“Provocative. … Heart-wrenching. … Remarkable. … Richtel is a gifted storyteller. … A story about cutting-edge science, humanely told.” (Matt McCarthy, USA Today)“Vividly told. ... Explicates for the lay reader the intricate biology of our immune system. ... Richtel succeeds in this formidable task.” (JEROME GROOPMAN, New York Review of Books)“In this thorough investigation, Richtel details the explosion of knowledge over the past 70 years. ... He weaves into his narrative four case studies [that] add a moving personal dimension.” (BBC, “10 Books to Read This Month”)“Matt Richtel’s An Elegant Defense is a comprehensive and engaging primer on the body’s ‘ever-vigilant, omnipresent peacekeeping force.’ The immune system plays an essential role in fighting infections and cancer and in regulating our normal health. Read this superb book to better understand one of the enduring mysteries of human biology.” (SANDEEP JAUHAR, New York Times bestselling author of Heart: A History)“An expert examination of the immune system. … Richtel illuminates a complex subject so well that even physicians will learn.” (Kirkus, STARRED review)“Richtel approaches this essential subject with awe, his writing meticulous and empathic.” (Booklist, STARRED Review)“Award-winning reporter Matt Richtel examines the scientific and human realities of immune anomaly through four case studies. … Through these harrowing accounts, Richtel interweaves the research history.” (Nature, “Best Science Picks”)“A deeply reported and entertainingly written exploration of the human immune system and how it works.” (USA Today (”5 Books Not to Miss”))
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About the Author
Matt Richtel is a Pulitzer Prize–winning New York Times reporter and bestselling nonfiction and mystery author. He lives in San Francisco with his wife, Meredith, a neurologist, and their two children. In his spare time, he plays tennis and piano and writes (not very good) songs. Visit him online at www.mattrichtel.wordpress.com.
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Product details
Paperback: 576 pages
Publisher: HarperLuxe; Larger Print edition (March 12, 2019)
Language: English
ISBN-10: 0062699105
ISBN-13: 978-0062699107
Product Dimensions:
6 x 1.3 x 9 inches
Shipping Weight: 1.2 pounds (View shipping rates and policies)
Average Customer Review:
4.8 out of 5 stars
10 customer reviews
Amazon Best Sellers Rank:
#24,227 in Books (See Top 100 in Books)
In An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives, Richtel explains how medical research has overturned what we think we know about ourselves and our environment The book tells the story of four individuals whose immune systems were the key to their health — or to their illness; their stories are used to explore, in clear terms, the history of the research into the immune system and exactly how we now understand it to work.An interesting read regarding our understanding of the immune system and how society is effecting it.
Fantastic read! Richtel compellingly interweaves the science and history of immunology into the lives of four patients, each dealing with different aspects of immune function & dysfunction: overreaction, underreaction, recognizing self as enemy, recognizing enemy as self, and much more.It's an ambitious premise, and he pulls it off magnificently. I had to read the whole thing in one sitting. What makes the book supremely compelling is the vivid story of his childhood friend Jason's cancer treatment. Jason not only granted Richtel access to all of his medical records and doctor visits, but also had the kind of revelatory long talks and walks that only best friends can have. The result is an unusually well-rounded psychological portrait of a patient, along with the intricately winding course of his treatment that reads like a detective story, except real. The tales are poignant, and I found myself crying (and laughing) multiple times.As someone who's studied immunology twice, as both biologist and medical student, I found the book a useful refresher of immune function, with some updates into the 21st century. If you do not have a background in immunology, however, this is a must-read. Every day, billions of malign agents are trying to kill you, and fail only because your immune system is on guard. How does it recognize and ward off the infinitude of potential pathogens that could invade you and lay you low? How can it tell outsiders from insiders? And how does it put the brakes on itself when it's in full defense mode?The inner workings the immune system should make you gasp with wonder at the beauty of how nature could come up with something so insanely intricate and effective. It's literally keeping you alive every moment of every day, so do yourself a favor and read up on your T cells, B cells, dendritic cells, interferons, and cytokines so you can better appreciate this miracle that's protecting your body night and day.-- Ali Binazir, M.D., M.Phil., Happiness Engineer and author of The Tao of Dating: The Smart Woman's Guide to Being Absolutely Irresistible, the highest-rated dating book on Amazon, and Should I Go to Medical School?: An Irreverent Guide to the Pros and Cons of a Career in Medicine
Tremendously educational book with lots of science. Written with great stories in a conversational style that makes it easy to follow the technical info.
Must read for anyone interested in the immune system. Couldn’t put the book down for several days until it was finished.
Bought it as a gift
Wow!I’m almost at a loss for words to describe AN ELEGANT DEFENSE and emphasize not only how important but also how interesting this book is. So I begin my comments with an exclamation (wow).This is a science book. But (whoa, don’t go away) it is probably unlike any science book you’ve had experience with. It is casual and easy to understand. And even though it does contain scientific words, Matt Richtel occasionally reminds the reader what they mean and how they are applicable to what he then describes.I am not a scientific or medical person. I only decided to read this because Richtel is a Pulitzer Prize winner for his A DEADLY WANDERING. And was I surprised that someone could make the science of the immune system so darned interesting. Honestly, it was as if I was reading an exciting thriller last night when I stayed up reading this book until I fell asleep sometime past midnight. Maybe that’s because he gives real-life examples of what he is talking about.Richtel divides AN ELEGANT DEFENSE into five parts, each perfectly named (as are the chapters). First he introduces us to four people, examples for “the extraordinary new science of the immune system.†Next comes the science, which Richtel still manages to keep casual, even humorous at times. And he sometimes adds to this part other real-life examples. The remainder of the book concentrates more on the people he began with.Much, maybe most, of AN ELEGANT DEFENSE is personal. Yes, I learned a lot. But I think, even with these readable explanations and examples showing how our immune systems are so important to everything about our bodies, this book absorbed me because Richtel makes it personal, especially Jason. Jason is the reason I stayed awake past midnight last night.I won the ARC of AN ELEGANT DEFENSE through librarything.com.
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